Determining Gender Sex of a Kitten This information is not meant to be a substitute for veterinary care. Always follow the instructions provided by your veterinarian. You just brought home a kitten that you intend to name Sam but your roommate tells you that you had better consider the name Samantha instead. Determining the sex gender of a kitten is easy when you know what to look for. Lift the kitten's tail.
There is not too much that can go wrong when attempting to determine the sex of kittens, however, I will draw your attention to a couple of important kitten-handling dos and do nots, which shouldbe taken into consideration. Handle your kittens gently. Rest your kittens on a clean towel on their bellies and lift their tails gently to examine their genitals. Where possible, wait to sex kittens until they are over weeks of age. Make sure that your cat the mother cat is comfortable with you handling her kittens before proceeding to touch them.
Inspecting a small kitten might involve simply holding it gently on its back in the palm of your hand. Older kittens may do better standing on a firm surface and having their tails gently elevated to expose their perineal area. In females, the genital opening is immediately below the anus. In intact adult males, the testicles can be observed between the two openings. Most calico and tortoise shell kitties are females, and orange cats are typically male.